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1

Production and purification of serotype 1, 2, and 5 recombinant adeno-associated viral vectors

Sergei Zolotukhin, Mark Potter, Irene Zolotukhin, Yoshihisa Sakai, Scott Loiler, Thomas J Fraites Jr., Vince A Chiodo, Tina Phillipsberg, Nicholas Muzyczka, William W Hauswirth, Terance R Flotte, Barr

Journal:

Year:

2002

Language:

english

File:

PDF, 425 KB

english, 2002

2

[Current Topics in Microbiology and Immunology] Viral Expression Vectors Volume 158 || Use of Adeno-Associated Virus as a General Transduction Vector for Mammalian Cells

Muzyczka, Nicholas

Year:

1992

Language:

english

File:

PDF, 3.78 MB

english, 1992

3

Recombinant adeno-associated virus purification using novel methods improves infectious titer and yield

Zolotukhin, S, Byrne, B J, Mason, E, Zolotukhin, I, Potter, M, Chesnut, K, Summerford, C, Samulski, R J, Muzyczka, N

Journal:

Year:

1999

Language:

english

File:

PDF, 631 KB

english, 1999

4

10 Adeno-associated virus-mediated knockdown of pyruvate dehydrogenase E1 in specific regions of the rat brain

Carolyn Ojano-Dirain, Lyudmyla G. Glushakova, Nicholas Muzyczka, Arun Srivastava, Peter W. Stacpoole

Journal:

Year:

2010

Language:

english

File:

PDF, 60 KB

english, 2010

5

AAV-Mediated Gene Therapy for Research and Therapeutic Purposes

Samulski, R. Jude, Muzyczka, Nicholas

Journal:

Annual Review of Virology

Year:

2014

Language:

english

File:

PDF, 2.09 MB

english, 2014

6

Structure and Dynamics of Adeno-Associated Virus Serotype 1 VP1-Unique N-Terminal Domain and Its Role in Capsid Trafficking

Venkatakrishnan, B., Yarbrough, J., Domsic, J., Bennett, A., Bothner, B., Kozyreva, O. G., Samulski, R. J., Muzyczka, N., McKenna, R., Agbandje-McKenna, M.

Journal:

Journal of Virology

Year:

2013

Language:

english

File:

PDF, 2.98 MB

english, 2013

7

Behavior of Cast‐Iron Spillway Gate Wheels

Polyzois, Dimos, Muzyczka, Walter J.

Journal:

Journal of Materials in Civil Engineering

Year:

1994

Language:

english

File:

PDF, 1.36 MB

english, 1994

8

AAV: An Overview of Unanswered Questions

Berns, Kenneth I., Muzyczka, Nicholas

Journal:

Human Gene Therapy

Year:

2017

Language:

english

File:

PDF, 381 KB

english, 2017

9

Wisc Characteristics of Reading Disabled Children Identified by Three Objective Methods

Muzyczka, Marjorie J., Erickson, Marilyn T.

Journal:

Perceptual and Motor Skills

Year:

1976

Language:

english

File:

PDF, 337 KB

english, 1976

10

Biodistribution of Adeno-Associated Virus Type 2 with Mutations in the Capsid that Contribute to Heparan Sulfate Proteoglycan Binding

Gorbatyuk, Oleg S., Warrington, Kenneth H., Gorbatyuk, Marina S., Zolotukhin, Irene, Lewin, Alfred S., Muzyczka, Nicholas

Journal:

Year:

2019

File:

PDF, 3.73 MB

2019

11

Cre-mediated recombination in the pituitary gland

Lisa J. Cushman, Heather L. Burrows, Audrey F. Seasholtz, Mark Lewandoski, Nicholas Muzyczka, Sally A. Camper

Journal:

Year:

2000

Language:

english

File:

PDF, 1.00 MB

english, 2000

12

Adeno-Associated Virus Rep78/Rep68 Promotes Localized Melting of the Rep Binding Element in the Absence of Adenosine Triphosphate

Hua Jane Lou, J. Rodney Brister, Jianwei Jeffery Li, Weijun Chen, Nicholas Muzyczka, Weihong Tan

Journal:

Year:

2004

Language:

english

File:

PDF, 178 KB

english, 2004

13

Finite element analysis of cast iron spillway gate wheels

D. Polyzois, W.J. Muzyczka, J.D. Garroni

Journal:

Computers & Structures

Year:

1995

Language:

english

File:

PDF, 737 KB

english, 1995

14

Comparison of the DNA sequence and secondary structure of the herpes simplex virus L/S junction and the adeno-associated virus terminal repeat

Mark Rayfield, George S. Michaels, Richard Feldmann, Nicholas Muzyczka

Journal:

Journal of Theoretical Biology

Year:

1985

Language:

english

File:

PDF, 1.21 MB

english, 1985

15

Developing VDEPT for DT-diaphorase (NQO1) using an AAV vector plasmid

Kenneth H Warrington Jr., Christian Teschendorf, Longguang Cao, Nicholas Muzyczka, Dietmar W Siemann

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

1998

Language:

english

File:

PDF, 106 KB

english, 1998

16

Restriction endonuclease mapping of the colicin Ib plasmid

Satish Walia, Glenda Dunn, Kathryn Rose, Thomas Pinkerton, Nicholas Muzyczka, Donna Duckworth

Journal:

Molecular Genetics and Genomics

Year:

1982

Language:

english

File:

PDF, 520 KB

english, 1982

17

Adeno-associated virus–mediated gene transfer of endostatin inhibits angiogenesis and tumor growth in vivo

Shi, Wenyin, Teschendorf, Christian, Muzyczka, Nicholas, Siemann, Dietmar W

Journal:

Cancer Gene Therapy

Year:

2002

Language:

english

File:

PDF, 827 KB

english, 2002

18

Efficient transduction of green fluorescent protein in spinal cord neurons using adeno-associated virus vectors containing cell type-specific promoters

Peel, A L, Zolotukhin, S, Schrimsher, G W, Muzyczka, N, Reier, P J

Journal:

Year:

1997

Language:

english

File:

PDF, 1010 KB

english, 1997

19

Long-term in vivo cochlear transgene expression mediated by recombinant adeno-associated virus

Lalwani, A K, Walsh, B J, Reilly, P G, Carvalho, G J, Zolotukhin, S, Muzyczka, N, Mhatre, A N

Journal:

Year:

1998

Language:

english

File:

PDF, 998 KB

english, 1998

20

High-titer recombinant adeno-associated virus production utilizing a recombinant herpes simplex virus type I vector expressing AAV-2 Rep and Cap

Conway, J E, Rhys, CMJ ap, Zolotukhin, I, Zolotukhin, S, Muzyczka, N, Hayward, G S, Byrne, B J

Journal:

Year:

1999

Language:

english

File:

PDF, 307 KB

english, 1999

21

Observed incidence of tumorigenesis in long-term rodent studies of rAAV vectors

Donsante, A, Vogler, C, Muzyczka, N, Crawford, J M, Barker, J, Flotte, T, Campbell-Thompson, M, Daly, T, Sands, M S

Journal:

Year:

2001

Language:

english

File:

PDF, 586 KB

english, 2001

22

NGF gene transfer to intrinsic basal forebrain neurons increases cholinergic cell size and protects from age-related, spatial memory deficits in middle-aged rats

Ronald L Klein, Aaron C Hirko, Craig A Meyers, Jeremy R Grimes, Nicholas Muzyczka, Edwin M Meyer

Journal:

Year:

2000

Language:

english

File:

PDF, 736 KB

english, 2000

23

Generation of aberrant sprouting in the adult rat brain by GAP-43 somatic gene transfer

Ronald L Klein, Robert K McNamara, Michael A King, Robert H Lenox, Nicholas Muzyczka, Edwin M Meyer

Journal:

Year:

1999

Language:

english

File:

PDF, 2.30 MB

english, 1999

24

Prevention of 6-hydroxydopamine-induced rotational behavior by BDNF somatic gene transfer

Ronald L. Klein, Mark H. Lewis, Nicholas Muzyczka, Edwin M. Meyer

Journal:

Year:

1999

Language:

english

File:

PDF, 706 KB

english, 1999

25

Neuron-Specific Transduction in the Rat Septohippocampal or Nigrostriatal Pathway by Recombinant Adeno-associated Virus Vectors

Ronald L. Klein, Edwin M. Meyer, Alyson L. Peel, Sergei Zolotukhin, Craig Meyers, Nicholas Muzyczka, Michael A. King

Journal:

Experimental Neurology

Year:

1998

Language:

english

File:

PDF, 264 KB

english, 1998

26

Suppression of Insult-Induced Neurogenesis in Adult Rat Brain by Brain-Derived Neurotrophic Factor

Elin Larsson, Ronald J. Mandel, Ronald L. Klein, Nicholas Muzyczka, Olle Lindvall, Zaal Kokaia

Journal:

Experimental Neurology

Year:

2002

Language:

english

File:

PDF, 306 KB

english, 2002

27

Neuropathological and Behavioral Consequences of Adeno-Associated Viral Vector-Mediated Continuous Intrastriatal Neurotrophin Delivery in a Focal Ischemia Model in Rats

Gunnar Andsberg, Zaal Kokaia, Ronald L. Klein, Nicholas Muzyczka, Olle Lindvall, Ronald J. Mandel

Journal:

Neurobiology of Disease

Year:

2002

Language:

english

File:

PDF, 512 KB

english, 2002

28

Recombinant adeno-associated viral vector (rAAV) delivery of GDNF provides protection against 6-OHDA lesion in the common marmoset monkey (Callithrix jacchus)

Andisheh Eslamboli, Rosalyn M Cummings, Rosalind M Ridley, Harry F Baker, Nicholas Muzyczka, Corinna Burger, Ronald J Mandel, Deniz Kirik, Lucy E Annett

Journal:

Experimental Neurology

Year:

2003

Language:

english

File:

PDF, 620 KB

english, 2003

29

rAAV-mediated nigral human parkin over-expression partially ameliorates motor deficits via enhanced dopamine neurotransmission in a rat model of Parkinson's disease

Fredric P. Manfredsson, Corinna Burger, Layla F. Sullivan, Nicholas Muzyczka, Alfred S. Lewin, Ronald J. Mandel

Journal:

Experimental Neurology

Year:

2007

Language:

english

File:

PDF, 1.56 MB

english, 2007

30

Heparin binding induces conformational changes in Adeno-associated virus serotype 2

Hazel C. Levy, Valorie D. Bowman, Lakshmanan Govindasamy, Robert McKenna, Kevin Nash, Kenneth Warrington, Weijun Chen, Nicholas Muzyczka, Xiaodong Yan, Timothy S. Baker, Mavis Agbandje-McKenna

Journal:

Journal of Structural Biology

Year:

2009

Language:

english

File:

PDF, 750 KB

english, 2009

31

Hypothalamic rAAV-mediated GDNF gene delivery ameliorates age-related obesity

Nihal Tümer, Philip J. Scarpace, M. Devrim Dogan, Christopher S. Broxson, Michael Matheny, David M. Yurek, Carmen S. Peden, Corinna Burger, Nicholas Muzyczka, Ronald J. Mandel

Journal:

Neurobiology of Aging

Year:

2006

Language:

english

File:

PDF, 537 KB

english, 2006

32

Myosin IIb Regulates Actin Dynamics during Synaptic Plasticity and Memory Formation

Christopher S. Rex, Cristin F. Gavin, Maria D. Rubio, Eniko A. Kramar, Lulu Y. Chen, Yousheng Jia, Richard L. Huganir, Nicholas Muzyczka, Christine M. Gall, Courtney A. Miller, Gary Lynch, Gavin Rumba

Journal:

Year:

2010

Language:

english

File:

PDF, 1.66 MB

english, 2010

33

Changes in transcription within the CA1 field of the hippocampus are associated with age-related spatial learning impairments

Corinna Burger, M. Cecilia López, Joyce A. Feller, Henry V. Baker, Nicholas Muzyczka, Ronald J. Mandel

Journal:

Neurobiology of Learning and Memory

Year:

2007

Language:

english

File:

PDF, 2.40 MB

english, 2007

34

Genome-wide analysis of aging and learning-related genes in the hippocampal dentate gyrus

Corinna Burger, M. Cecilia Lopez, Henry V. Baker, Ronald J. Mandel, Nick Muzyczka

Journal:

Neurobiology of Learning and Memory

Year:

2008

Language:

english

File:

PDF, 4.39 MB

english, 2008

35

Enhanced expression of Pctk1, Tcf12 and Ccnd1 in hippocampus of rats: Impact on cognitive function, synaptic plasticity and pathology

Ke Wu, Shoudong Li, Karthik Bodhinathan, Craig Meyers, Weijun Chen, Martha Campbell-Thompson, Lauren McIntyre, Thomas C. Foster, Nicholas Muzyczka, Ashok Kumar

Journal:

Neurobiology of Learning and Memory

Year:

2012

Language:

english

File:

PDF, 1.10 MB

english, 2012

36

An animal model of PDH deficiency using AAV8-siRNA vector-mediated knockdown of pyruvate dehydrogenase E1α

Carolyn Ojano-Dirain, Lyudmyla G. Glushakova, Li Zhong, Sergei Zolotukhin, Nicholas Muzyczka, Arun Srivastava, Peter W. Stacpoole

Journal:

Molecular Genetics and Metabolism

Year:

2010

Language:

english

File:

PDF, 1.42 MB

english, 2010

37

Long-term differential modulation of genes encoding orexigenic and anorexigenic peptides by leptin delivered by rAAV vector in ob/ob mice: Relationship with body weight change

H Dhillon, Y.-L Ge, R.M Minter, V Prima, L.L Moldawer, N Muzyczka, S Zolotukhin, P.S Kalra, S.P Kalra

Journal:

Regulatory Peptides

Year:

2000

Language:

english

File:

PDF, 1.48 MB

english, 2000

38

Central leptin gene therapy suppresses body weight gain, adiposity and serum insulin without affecting food consumption in normal rats: a long-term study

H Dhillon, S.P Kalra, V Prima, S Zolotukhin, P.J Scarpace, L.L Moldawer, N Muzyczka, P.S Kalra

Journal:

Regulatory Peptides

Year:

2001

Language:

english

File:

PDF, 467 KB

english, 2001

39

Long-term actions of vector-derived nerve growth factor or brain-derived neurotrophic factor on choline acetyltransferase and Trk receptor levels in the adult rat basal forebrain

R.L. Klein, D.F. Muir, M.A. King, A.L. Peel, S. Zolotukhin, J.C. Möller, A. Krüttgen, J.V. Heymach Jr, N. Muzyczka, E.M. Meyer

Journal:

Year:

1999

Language:

english

File:

PDF, 1.44 MB

english, 1999

40

Green fluorescent protein as a reporter for gene transfer studies in the cochlea

Anil K. Lalwani, Jay J. Han, Bong J. Walsh, Sergei Zolotukhin, Nicholas Muzyczka, Anand N. Mhatre

Journal:

Hearing Research

Year:

1997

Language:

english

File:

PDF, 749 KB

english, 1997

41

Gene therapy for murine mucopolysaccharidosis type VII

Mark S Sands, John H Wolfe, Edward H Birkenmeier, Jane E Barker, Carole Vogler, William S Sly, Torayuki Okuyama, Brian Freeman, Andrew Nicholes, Nicholas Muzyczka, Patricia L Chang, Helena R Axelrod

Journal:

Neuromuscular Disorders

Year:

1997

Language:

english

File:

PDF, 584 KB

english, 1997

42

The phosphorylation state of Ser-129 in human -synuclein determines neurodegeneration in a rat model of Parkinson disease

Gorbatyuk, O. S., Li, S., Sullivan, L. F., Chen, W., Kondrikova, G., Manfredsson, F. P., Mandel, R. J., Muzyczka, N.

Journal:

Proceedings of the National Academy of Sciences

Year:

2008

Language:

english

File:

PDF, 1.16 MB

english, 2008

43

Characterization of the adenoassociated virus Rep protein complex formed on the viral origin of DNA replication

Zengi Li, J.Rodney Brister, Dong-Soo Im, Nicholas Muzyczka

Journal:

Year:

2003

Language:

english

File:

PDF, 583 KB

english, 2003

44

Studies on the biochemical basis of spontaneous mutation: II. The incorporation of a base and its analogue into DNA by wild-type, mutator and antimutator DNA polymerases

Maurice J. Bessman, Nicholas Muzyczka, Myron F. Goodman, Ronald L. Schnaar

Journal:

Journal of Molecular Biology

Year:

1974

Language:

english

File:

PDF, 907 KB

english, 1974

45

Studies on the biochemical basis of spontaneous mutation: III. Rate model for DNA polymerase-effected nucleotide misincorporation

Myron F. Goodman, Willis C. Gore, Nicholas Muzyczka, Maurice J. Bessman

Journal:

Journal of Molecular Biology

Year:

1974

Language:

english

File:

PDF, 808 KB

english, 1974

46

Gene therapy delivery of endostatin enhances the treatment efficacy of radiation

Wenyin Shi, Christian Teschendorf, Nicholas Muzyczka, Dietmar W Siemann

Journal:

Radiotherapy and Oncology

Year:

2003

Language:

english

File:

PDF, 170 KB

english, 2003

47

Molecular cloning, overexpression, and an efficient one-step purification of α5β1 integrin

Tartaglia, Lawrence J., Bennett, Antonette, Plattner, Alexander S., Muzyczka, Nicholas, Ling, Chen, Srivastava, Arun, Agbandje-McKenna, Mavis

Journal:

Protein Expression and Purification

Year:

2013

Language:

english

File:

PDF, 2.26 MB

english, 2013

48

OneBac: Platform for Scalable and High-Titer Production of Adeno-Associated Virus Serotype 1–12 Vectors for Gene Therapy

Mietzsch, Mario, Grasse, Sabrina, Zurawski, Catherine, Weger, Stefan, Bennett, Antonette, Agbandje-McKenna, Mavis, Muzyczka, Nicholas, Zolotukhin, Sergei, Heilbronn, Regine

Journal:

Human Gene Therapy

Year:

2014

Language:

english

File:

PDF, 349 KB

english, 2014

49

Rescue of adeno-associated virus from recombinant plasmids: Gene correction within the terminal repeats of AAV

Samulski, Richard J., Srivastava, Arun, Berns, Kenneth I., Muzyczka, Nicholas

Journal:

Year:

1983

Language:

english

File:

PDF, 3.41 MB

english, 1983

50

In vitro resolution of covalently joined AAV chromosome ends

Snyder, Richard O., Samulski, Richard Jude, Muzyczka, Nicholas

Journal:

Year:

1990

Language:

english

File:

PDF, 3.29 MB

english, 1990